The fundamental processes of energy production in cells involve complex pathways that generate ATP through different mechanisms.
Cellular respiration and fermentation represent two distinct pathways cells use to produce energy. While cellular respiration requires oxygen and produces more ATP through complete glucose breakdown, fermentation occurs without oxygen and yields less energy. In cellular respiration, glucose is fully broken down into carbon dioxide and water through glycolysis, the citric acid cycle, and the electron transport chain. This process generates up to 38 ATP molecules. Fermentation, however, only partially breaks down glucose and produces just 2 ATP molecules along with either lactic acid or ethanol as byproducts.
The electron transport chain relies heavily on electron carriers like NAD and FAD to transfer high-energy electrons through a series of protein complexes in the mitochondrial membrane. These carriers undergo continuous cycles of oxidation and reduction in cellular respiration - NAD+ accepts electrons and hydrogen to become NADH, while FAD accepts electrons to become FADH2. As electrons move down the transport chain, their energy is used to pump hydrogen ions across the membrane, creating a concentration gradient. This gradient drives ATP synthesis through chemiosmosis when protons flow back across the membrane through ATP synthase. This intricate process of electron transport and proton pumping is essential for generating most of the ATP produced during cellular respiration, making it a crucial energy-producing pathway in cells. The efficiency of this system allows organisms to maximize energy extraction from glucose, supporting various life processes and cellular functions.