Risk Factors and Diagnosis

Understanding the risk factors and diagnostic process is crucial for early intervention and management. While the exact cause remains unknown, several factors contribute to increased risk.

Highlight: Key risk factors include advancing age, family history, previous head injuries, and cardiovascular health issues.

Definition: Definitive diagnosis requires examination of brain tissue, though symptoms are monitored over time.

Example: Associated conditions like depression and high blood pressure may increase risk of developing Alzheimer's.

Understanding the Foundations of Alzheimer's Disease

The first stage of Alzheimer's disease involves complex changes within the brain structure and function. The disease begins with toxic changes in the brain, specifically in the hippocampus, leading to memory formation difficulties.

Definition: Alzheimer's disease is a progressive neurological condition where symptoms gradually worsen over several years.

Highlight: During the preclinical stage, while patients appear symptom-free, significant brain changes are already occurring through protein deposits and neuron death.

Example: Early symptoms can include confusion, disorientation, and getting lost in familiar places, often mistaken for normal aging.

Vocabulary: Amyloid plaques and tau tangles are abnormal protein deposits that form throughout the brain, leading to neuron death.