Understanding Cell Division and Mitosis
Ever wonder how you grew from a tiny baby to your current height? Cell division is the answer! While some cells (like certain neurons in your brain) eventually stop dividing, most cells have the primary goal of multiplying to create new daughter cells identical to the original.
Before division begins, cells prepare by replicating their DNA during the S phase of the cell cycle. During this critical phase, chromosomes that started as single strands of DNA become chromosomes with two strands (called sister chromatids). This duplication ensures each new cell gets a complete set of genetic information.
The actual nuclear division process, called mitosis, happens through five distinct phases: prophase, prometaphase, metaphase, anaphase, and telophase. During prophase, duplicated chromosomes become visible and mitotic spindles form. In prometaphase, kinetochore proteins form around centromeres. By metaphase, the nuclear envelope breaks down and spindle fibers attach to chromosomes. During anaphase, sister chromatids are pulled apart, and in telophase, new nuclear envelopes form around the separated chromosomes. The cell then physically divides during cytokinesis.
Fun Fact: Scientists often study cell division by examining root tips of plants. Since roots grow from their tips, these areas contain many actively dividing cells, making them perfect for observing mitosis in action!
After division is complete, cells enter the G0 phase until they're ready to divide again. When division begins anew, cells progress through G1 (preparation), S (DNA replication), and G2 (growth) phases before starting mitosis again. This continuous cycle ensures organisms can grow, heal wounds, and replace aging cells throughout life.