Enzyme Sensitivity
Since enzymes are proteins, they can also be denatured by extreme conditions. When an enzyme denatures, its active site changes shape, and it can no longer bind to its substrate.
Temperature, pH, and certain chemicals can all affect enzyme function. Each enzyme works best at specific conditions - for example, digestive enzymes in your stomach function well in acidic environments, while enzymes in your blood need a neutral pH.
In lab experiments, you can observe enzyme activity by watching how quickly they break down substrates. For instance, the enzyme catalase (found in liver cells) breaks down hydrogen peroxide into water and oxygen gas, creating visible bubbles.
Application: Understanding enzyme sensitivity helps explain why your body temperature and pH must be carefully regulated - even small changes can slow down or stop essential enzymatic reactions!