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Higher Biology Gene Expression & Protein Synthesis Notes with Diagrams

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sarah

1/11/2023

Biology

Gene Expression - Higher Biology

Higher Biology Gene Expression & Protein Synthesis Notes with Diagrams

Gene expression is a fundamental process in biology involving transcription and translation to synthesize proteins from DNA. This summary covers the key steps, RNA types, and important concepts in protein synthesis.

Bold keywords: Higher biology gene expression notes, Protein synthesis higher Biology, Transcription and translation steps, RNA splicing, mRNA splicing

  • Protein synthesis occurs in two main stages: transcription and translation
  • Three types of RNA are involved: mRNA, tRNA, and rRNA
  • Transcription produces a primary mRNA transcript, which undergoes splicing
  • Translation uses the mature mRNA to synthesize proteins on ribosomes
...

1/11/2023

289

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

View

Transcription Process

The transcription and translation steps begin with the synthesis of mRNA. This process occurs in the nucleus and involves several key steps:

  1. RNA polymerase moves along the DNA, unwinding the double helix and breaking hydrogen bonds between bases.
  2. Free RNA nucleotides are added to the growing mRNA strand through complementary base pairing.
  3. The mRNA strand continues to grow from the 5' end to the 3' end until a specific sequence called a stop codon is reached.

Vocabulary: The primary transcript of mRNA is the initial RNA molecule produced during transcription, before any modifications.

The resulting mRNA strand, known as the primary transcript, separates from the DNA template. This primary transcript will undergo further processing before it can be used for protein synthesis.

Highlight: The direction of mRNA synthesis 5to35' to 3' is important for understanding the subsequent steps in protein synthesis higher Biology.

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

View

RNA Processing and Splicing

After transcription, the primary mRNA transcript undergoes processing to form the mature mRNA transcript. This process is crucial in Higher biology gene expression and involves:

  1. Identification of codons: Each triplet of bases on the mRNA molecule is called a codon and codes for a specific amino acid.
  2. Removal of introns and splicing of exons: Introns are non-coding regions of the primary mRNA transcript and are removed. Exons are coding regions that are spliced joinedtogetherjoined together to form the mature mRNA transcript.

Definition: RNA splicing is the process of removing introns and joining exons to form a mature mRNA transcript.

Highlight: The order of exons remains unchanged during splicing, ensuring the correct sequence for protein synthesis.

An important concept in gene expression is alternative splicing:

Example: The same gene can produce different proteins by treating different regions as introns and exons. This means a single primary mRNA transcript has the potential to produce several mature mRNA transcripts depending on which exons are retained.

This process of mRNA splicing and alternative splicing allows for greater protein diversity from a limited number of genes, highlighting the complexity of gene expression in higher organisms.

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

View

Translation Process

Translation is the second major stage in protein synthesis higher Biology. It occurs in the cytoplasm and involves the following steps:

  1. The mature mRNA transcript attaches to a ribosome in the cytoplasm.
  2. The start codon initiates protein synthesis.
  3. Complementary tRNA anticodons attach to the mRNA strand, bringing specific amino acids to form the protein molecule.
  4. Peptide bonds join the amino acid molecules. Each tRNA molecule leaves the ribosome once its amino acid is attached.
  5. A stop codon ends protein synthesis.

Vocabulary: Anticodons are sequences on tRNA molecules that are complementary to codons on mRNA.

Highlight: The ribosome plays a crucial role in translation by providing the site for mRNA and tRNA interaction and facilitating peptide bond formation.

This process of translation results in the synthesis of a specific protein based on the genetic information originally encoded in the DNA and transcribed into mRNA. Understanding these transcription and translation steps is fundamental to comprehending gene expression and protein synthesis in Higher Biology.

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Biology

289

Jan 11, 2023

4 pages

Higher Biology Gene Expression & Protein Synthesis Notes with Diagrams

user profile picture

sarah

@sarah______

Gene expression is a fundamental process in biology involving transcription and translation to synthesize proteins from DNA. This summary covers the key steps, RNA types, and important concepts in protein synthesis.

Bold keywords: Higher biology gene expression notes, ... Show more

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

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Transcription Process

The transcription and translation steps begin with the synthesis of mRNA. This process occurs in the nucleus and involves several key steps:

  1. RNA polymerase moves along the DNA, unwinding the double helix and breaking hydrogen bonds between bases.
  2. Free RNA nucleotides are added to the growing mRNA strand through complementary base pairing.
  3. The mRNA strand continues to grow from the 5' end to the 3' end until a specific sequence called a stop codon is reached.

Vocabulary: The primary transcript of mRNA is the initial RNA molecule produced during transcription, before any modifications.

The resulting mRNA strand, known as the primary transcript, separates from the DNA template. This primary transcript will undergo further processing before it can be used for protein synthesis.

Highlight: The direction of mRNA synthesis 5to35' to 3' is important for understanding the subsequent steps in protein synthesis higher Biology.

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

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Access to all documents

Improve your grades

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RNA Processing and Splicing

After transcription, the primary mRNA transcript undergoes processing to form the mature mRNA transcript. This process is crucial in Higher biology gene expression and involves:

  1. Identification of codons: Each triplet of bases on the mRNA molecule is called a codon and codes for a specific amino acid.
  2. Removal of introns and splicing of exons: Introns are non-coding regions of the primary mRNA transcript and are removed. Exons are coding regions that are spliced joinedtogetherjoined together to form the mature mRNA transcript.

Definition: RNA splicing is the process of removing introns and joining exons to form a mature mRNA transcript.

Highlight: The order of exons remains unchanged during splicing, ensuring the correct sequence for protein synthesis.

An important concept in gene expression is alternative splicing:

Example: The same gene can produce different proteins by treating different regions as introns and exons. This means a single primary mRNA transcript has the potential to produce several mature mRNA transcripts depending on which exons are retained.

This process of mRNA splicing and alternative splicing allows for greater protein diversity from a limited number of genes, highlighting the complexity of gene expression in higher organisms.

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

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Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Translation Process

Translation is the second major stage in protein synthesis higher Biology. It occurs in the cytoplasm and involves the following steps:

  1. The mature mRNA transcript attaches to a ribosome in the cytoplasm.
  2. The start codon initiates protein synthesis.
  3. Complementary tRNA anticodons attach to the mRNA strand, bringing specific amino acids to form the protein molecule.
  4. Peptide bonds join the amino acid molecules. Each tRNA molecule leaves the ribosome once its amino acid is attached.
  5. A stop codon ends protein synthesis.

Vocabulary: Anticodons are sequences on tRNA molecules that are complementary to codons on mRNA.

Highlight: The ribosome plays a crucial role in translation by providing the site for mRNA and tRNA interaction and facilitating peptide bond formation.

This process of translation results in the synthesis of a specific protein based on the genetic information originally encoded in the DNA and transcribed into mRNA. Understanding these transcription and translation steps is fundamental to comprehending gene expression and protein synthesis in Higher Biology.

Gene Expression
Protein Synthesis is in 2 stages:
Transcription. The synthesis of mRNA from a
section of DNA,
7
Translation - The synthesis

Sign up to see the contentIt's free!

Access to all documents

Improve your grades

Join milions of students

By signing up you accept Terms of Service and Privacy Policy

Transcription and RNA Structure

Transcription is the first stage of protein synthesis higher Biology, where mRNA is synthesized from a DNA template. This process involves RNA polymerase and occurs in the nucleus.

Definition: Transcription is the synthesis of mRNA from a section of DNA.

The structure of RNA differs from DNA in several key ways:

  • RNA is single-stranded, while DNA is double-stranded
  • RNA contains ribose sugar, whereas DNA has deoxyribose
  • RNA uses uracil instead of thymine as one of its bases

There are three types of RNA involved in gene expression:

  1. Messenger RNA mRNAmRNA: Carries genetic information from DNA to ribosomes
  2. Transfer RNA tRNAtRNA: Transports specific amino acids to ribosomes
  3. Ribosomal RNA rRNArRNA: Forms part of the ribosome structure

Highlight: Understanding the differences between DNA and RNA structure is crucial for comprehending the transcription and translation steps.

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Stefan S

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This app is really great. There are so many study notes and help [...]. My problem subject is French, for example, and the app has so many options for help. Thanks to this app, I have improved my French. I would recommend it to anyone.

Samantha Klich

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Wow, I am really amazed. I just tried the app because I've seen it advertised many times and was absolutely stunned. This app is THE HELP you want for school and above all, it offers so many things, such as workouts and fact sheets, which have been VERY helpful to me personally.

Anna

iOS user

I think it’s very much worth it and you’ll end up using it a lot once you get the hang of it and even after looking at others notes you can still ask your Artificial intelligence buddy the question and ask to simplify it if you still don’t get it!!! In the end I think it’s worth it 😊👍 ⚠️Also DID I MENTION ITS FREEE YOU DON’T HAVE TO PAY FOR ANYTHING AND STILL GET YOUR GRADES IN PERFECTLY❗️❗️⚠️

Thomas R

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Brad T

Android user

Not only did it help me find the answer but it also showed me alternative ways to solve it. I was horrible in math and science but now I have an a in both subjects. Thanks for the help🤍🤍

David K

iOS user

The app's just great! All I have to do is enter the topic in the search bar and I get the response real fast. I don't have to watch 10 YouTube videos to understand something, so I'm saving my time. Highly recommended!

Sudenaz Ocak

Android user

In school I was really bad at maths but thanks to the app, I am doing better now. I am so grateful that you made the app.

Greenlight Bonnie

Android user

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Marco B

iOS user

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Elisha

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This app is phenomenal down to the correct info and the various topics you can study! I greatly recommend it for people who struggle with procrastination and those who need homework help. It has been perfectly accurate for world 1 history as far as I’ve seen! Geometry too!

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iOS user