Nucleic Acids: Your Genetic Blueprint
The story of who you are is written in molecules called nucleic acids. Friedrich Miescher first identified these important compounds, while Phoebus Levene discovered their building blocks called nucleotides. The famous double helix structure of DNA was later uncovered by Watson, Crick, and Franklin.
Nucleotides, the monomers of nucleic acids, contain three key parts: a five-carbon sugar, a phosphate group, and a nitrogenous base. These components combine to form the two main types of nucleic acids: DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).
DNA and RNA differ in several important ways. DNA uses deoxyribose sugar and forms a double-stranded helix structure with thymine as one of its bases. RNA, however, contains ribose sugar, forms a single strand, and uses uracil instead of thymine. Both molecules use adenine, guanine, and cytosine as their other nitrogenous bases.
Remember this: The nucleotides in DNA pair up in specific ways - adenine always pairs with thymine, and guanine always pairs with cytosine. This is called complementary base pairing.